FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology Peptide inhibitors targeting FOXO4 p53 interactions and inducing senescent cancer cell specific apoptosis bioRxiv Senescent Cell Burden Is Reduced in Humans by Senolytic Drugs following Mayo Clinic research REGENHEALTHSOLUTIONS (RHS) A new class of drugs called senolytics works by hunting down and destroying senescent "zombie cells" that accumulate with age and drive wrinkles, weak bones, and organ decline. In an early human FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology