The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications FOXO4 DRI Legion inc FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology Directly from the paper covered by the post earlier, 90 year old equivalent mouse before and after treatment with FOXO4 D reverso inversio peptide, a FOXO4 inhibitor that blocks FOXO4 from arresting senescent cell apoptosis. Heterogeneity of Cellular Senescence, Senotyping, and Targeting by Senolytics and Senomorphics in Lung Diseases