What Are the Ingredients in Vape Juice? Going completely smoke free is difficult for many, but did you know that nicotine has been found in e cigarette liquids claiming to be 'nicotine free?' While e cigarettes don't contain tobacco, they may still What's in a vape? Don't Get Sucked In When you vape, you can breathe in the same harmful chemicals like in weedkiller. They just don't put it on the pack. Get the facts at health.tas.gov.au vaping What's in an e liquid or vape juice? The main ingredients are propylene glycol (PG) and vegetable glycerine (VG). These are solvents that are basically used to dissolve and carry the other ingredients.