Can You Donate Blood If You Smoke? What You Should Know Dr. Karuna Kumar Can You Give Blood If You Smoke Weed? Explained Clearly Most Commonly Googled Questions About Blood Donation Answered by the Experts, Part 2 Stanford Blood Center We all know smoking and vaping isn't great for your health. But it doesn't stop you from being a blood or plasma donor. Just make sure to wait one hour after donating Can you donate blood if you smoke?