Pigmented lesions of the oral mucosa and perioral tissues: a flow chart for the diagnosis and some recommendations for the management Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Labial melanotic macule Stock Image C057 2077 Science Photo Library Multifocal Pigmentation of the Oral Cavity The Journal of the American Dental Association Pigmented Lesions of the Oral Mucosa Pocket Dentistry