Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic Glutathione responsive nanomedicine leverages tumor redox imbalance for targeted cancer theranostics Discover Oncology Springer Nature Link Tumor targeted glutathione oxidation catalysis with ruthenium nanoreactors against hypoxic osteosarcoma Nature Communications Unveiling the Role of Glutathione S transferase Protein in Breast Cancer Drug Resistance: Insights into the Signaling Pathways and Therapeutic Implications ACS Pharmacology & Translational Science Pan Cancer Metabolic Signature Predicts Co Dependency on Glutaminase and De Novo Glutathione Synthesis Linked to a High Mesenchymal Cell State: Cell Metabolism