Oral Melanotic Macule: Symptoms and Treatment Skinsight Unlocking the Secrets of Melanotan II: Benefits, Risks, and How It Wor Mucosal melanocytic macules An oral melanotic macule is a harmless dark spot found on the lip, most often the lower lip, or inside the mouth, either on the gums, inside the cheek, or on the roof of the mouth. An oral melanotic Melanocytic Lesions A Guide to Clinical Differential Diagnosis of Oral Mucosal Lesions Continuing Education Course dentalcare.com