Melanotan II (Tan Jabs): Why They're Not Worth The Risk Your body already makes a hormone that tells your skin to tan. Melanotan 2 is a synthetic peptide engineered to mimic that hormone but in a version that's more potent and Changes in Oral Mucosa Associated with Melanotan II Injections: A Case Report Melanotan is not a tan. It's an unregulated peptide with real risk. As a dermatologist, here's the reality: It has been linked to new and changing moles including cases of Melanoma Fund Archives Melanoma Fund UK