Oral pathology: Noting a pigmented macule that often presents a diagnostic dilemma Registered Dental Hygienists Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Oral melanoacanthoma and oral melanotic macule: a report of 8 cases, review of the literature, and immunohistochemical analysis Vulvovaginal melanocytic lesions: a review Diagnostic Histopathology Pathology Outlines Melanotic macule
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