Sulforaphane potently activates the Nrf2 pathway, upregulating stress response genes similar to exercise and fasting., Why is this important?, It boosts glutathione, the bodys primary antioxidant, in Sulforaphane as a potential therapeutic agent: a comprehensive analysis of clinical trials and mechanistic insights Journal of Nutritional Science Cambridge Core What is Sulforaphane and what are its health benefits? Sulforaphane boosts our natural cellular defenses. It does this by activating Nrf2, our body's primary detoxification, anti inflammatory, and antioxidant pathway. Nrf2 turns on phase 2 detoxification enzymes, helping us deal with daily Sulforaphane, a phytochemical in broccoli sprouts, ameliorates obesity