Managing Cold Sore Flares in Adults Dr. Green Mom Herpes simplex virus protein UL56 inhibits cGAS Mediated DNA sensing to evade antiviral immunity ScienceDirect HERPES VIRUSES reactivation Sequence of events** When a person is suffering from chronic stress, excess Cortisol and Adrenaline with lowered Glutathione. Glutathione is the body's most important antioxidant. Insufficient Glutathione reduces the Lglutathione (GSH) is a tripeptide made of three amino acids (glutamate, cysteine and glycine) and is the body's main intracellular antioxidant. It neutralizes harmful oxygenbased molecules, protects proteins and cellular machinery from Engineering of a Single Conserved Amino Acid Residue of Herpes Simplex Virus Type 1 Thymidine Kinase Allows a Predominant Shift