Glutathione 500 mg Plus 21st Century Vitamins 21st Century Vitamins Key Benefits of Glutathione for Detox and Skin Health What Is Glutathione? 8 Health Benefits That Might Surprise You Glutathione. The Guardian Of Your Health Glutathione is a natural antioxidant your body makes, and it can influence melanin production which is why it's sometimes marketed for skin brightening. Oral supplements are mostly broken down in the