Dental Update Malignant oral melanoma: how to spot it and how it is managed Dental Update Oral melanoacanthoma and oral melanotic macule: a report of 8 cases, review of the literature, and immunohistochemical analysis Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Congenital Melanocytic Macule of the Tongue in a Newborn Cureus Oral melanotic macules are harmless but can be removed easily with laser treatment! Quick, safe, and effective. Say hello to even toned lips! #laser #candela #pico #lips #face #makeup #spa