How Common is Kidney Disease in Diabetes? Providence Specialty Centre Full article: Exogenous glutathione protects against gentamicin induced acute kidney injury by inhibiting NF B pathway, oxidative stress, and apoptosis and regulating PCNA For CKD, Id separate the proven support from the experimental but interesting category., Astragalus root extract is probably the most tried and true natural compound Id look at first. Theres Frontiers Advances in kidney disease: pathogenesis and therapeutic targets Downregulation of the kidney glucagon receptor, essential for renal function and systemic homeostasis, contributes to chronic kidney disease: Cell Metabolism