Melanosis Coli New England Journal of Medicine Frontiers Case report: Melanosis coli combined with colon cancer, causality or coincidence? Melanosis coli is dark brown black pigmentation of colorectal mucosa associated with chronic use of laxatives containing anthraquinone. Examples of such laxatives include senna and rhubarb derivatives. Clinical Importance: There is no association Pigmentation (melanosis) of the colon Stock Image Science Source Images Melanosis coli: a case report The Egyptian Journal of Internal Medicine Springer Nature Link
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