The Importance of Glutathione in Health and Healing Dr. Todd Maderis Could Tylenol be making your child's health worse? Acetaminophen is widely used for pain and fever relief, but research suggests it depletes glutathione, a powerful antioxidant essential for immune function, Glutathione IV Detox Your Shortcut to Feeling Fabulous Tylenol depletes glutathione your liver's most important protective antioxidant. Every dose chips away at it. So instead of taking lower doses every 46 hours, I recommend spacing to 1000mg every 8 hours. 7 Best Glutathione Supplements, According to Experts Vogue