Sex differences in glutathione metabolism and acetaminophen toxicity Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Data summary: IL 4 regulates glutathione levels in the liver and lung Download Scientific Diagram Dr. Laura E. Riley joined @GoodMorningAmerica recently to clear up some lingering confusion about Tylenol (acetaminophen) use during pregnancy. A new study from the University of London found that acetaminophen is safe Acetaminophen, also known as Tylenol, is used to help with pain & to reduce fever. However, taking too much acetaminophen can be harmful to the liver which filters out toxins &