The Role of Glutathione in Selected Viral Diseases Feeling worse before you feel better? It might be a Herx. Also called a Jarisch Herxheimer reaction, herxing happens when Lyme microbes are killed off and release toxins into your system, sparking a COVID19 and Lyme Disease Are You at Increased Risk? Dr. Todd Maderis Beating Lyme Disease Lyme disease and tick borne diseases are complicated illnesses and because of that, treatment can be complex. Patients who've gone through treatment will often say your symptoms get worse before they get better.