Sermorelin & Ipamorelin 10MG Raw Amino Sermorelin or Ipamorelin: Meaning, Differences, Benefits, Side Effects, and Which One May Be Better The Peptide Craze Ground Truths If you're considering peptide therapy, this is worth reading before you start. Peptides like sermorelin and ipamorelin work through pathways shaped by your existing hormone environment. Testosterone, thyroid function, and cortisol patterns We personally prefer Ipamorelin.