FOXO4 DRI alleviates age related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice Aging FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications Peptide inhibitors targeting FOXO4 p53 interactions and inducing senescent cancer cell specific apoptosis bioRxiv Frontiers FOXO4 DRI regulates endothelial cell senescence via the P53 signaling pathway
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foxo4-dri peptide senolytic 2023 2024 study FOXO4-DRI: The Senolytic Peptide That Targets Zombie Cells and Aging – Revolution Health & Wellness