Cagrilintide Dosage and Weight Loss Guide PEP DOSE Cagrilintide, an amylin analogue, is a promising medication for weight loss by enhancing satiety, delaying gastric emptying, and suppressing appetite. In my patients, I have also seen increased Recent advances in peptide based therapies for obesity and type 2 diabetes ScienceDirect When semaglutide and tirzepatide stop working for patients, Im adding in cagrilintide. Cagrilintide can add as much as 9% more weight loss to already used GLP1s such as semaglutide, tirzepatide or Cagrilintide (AM833) Long acting amylin analog. Beta cells make TWO hormones: insulin and amylin. Amylin slows stomach emptying and reduces appetite. Cagrilintide is a long acting synthetic amylin designed for once weekly dosing