Cagrilintide is an amylin analogue that helps regulate appetite. In a randomized trial of over 3400 patients who were overweight or obese and had 1 weight related complication, individuals assigned to a combination Cagrilintide lowers bodyweight through brain amylin receptors 1 and 3 eBioMedicine Once weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double blind, placebo controlled and active controlled, dose finding phase 2 trial The Lancet Cagrilintide: The Next Big Thing in Fat Loss or Just Hype? : r BoldReseachPeptides Structural and dynamic features of cagrilintide binding to calcitonin and amylin receptors Nature Communications