Good ol' paracetamol: 'But an overconsumption takes its toll' Journal of Anaesthesia Practice A 48 hour fast can turn standard Paracetamol into acute liver failure. Fasting depletes Glutathione, leaving the liver defenseless against toxic NAPQI. Review the latest guidelines on BMJ Best Practice: https: bestpractice.bmj.com topics en us 1010 File:Paracetamol metabolism.svg Wikimedia Commons Tylenol and glutathione, actually explainedhere's the bullet points: * Lots of concern raised on social media re: glutathione depletion and acetaminophen use * Glutathione is used in the metabolism Management of Acute Liver Failure (Chapter 6) Case Studies in Adult Intensive Care Medicine
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