Frontiers Nrf2 and Ferroptosis: A New Research Direction for Neurodegenerative Diseases NRF2 is part of a group of transcription factors called nuclear receptors The NRF2, Thioredoxin, and Glutathione System in Tumorigenesis and Anticancer Therapies Sulforaphane for Liver Health Sulforaphane is a food derived compound with a few core mechanisms. Nrf2 Activation for Phase II support being the primary mechanism. Increased glutathione production Increased phase II enzymes (GST, Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression Nature Communications