The mechanism by which excess GSH G6PD deficiency increases reactive Download Scientific Diagram Correcting glucose 6 phosphate dehydrogenase deficiency with a small molecule activator Nature Communications G6PD Deficiency Causes Haemolytic Anaemia Glucose 6 phosphate dehydrogenase is an enzyme in the hexose monophosphate shunt that synthesizes NADPH. The NADPH is used to convert oxidized glutathione (GSSG) to reduced glutathione ( Glucose 6 phosphate dehydrogenase deficiency pathophysiology wikidoc Correcting glucose 6 phosphate dehydrogenase deficiency with a small molecule activator Nature Communications