Frontiers Glutathione: Pharmacological aspects and implications for clinical use in non alcoholic fatty liver disease Gamma glutamyl transferase (GGT) and increased cardiometabolic stress. Download Scientific Diagram Crystal structures of glutamyltranspeptidase from Escherichia coli, a key enzyme in glutathione metabolism, and its reaction intermediate PNAS 8 But none of this explains WHY GGT is elevated at all 1GGT is maintaining glutathione stores 2If glutathione is, GGT goes 3No GGT? glutathione Q: What depletes glutathione? A: oxidative stress GGT (gamma glutamyltransferase): Diagnostic Significance and Clinical Insights Advanced Health Academy