L carnitine exerts a nutrigenomic effect via direct modulation of nuclear receptor signaling in adipocytes, hepatocytes and SKMC, demonstrating its nutritional impact ScienceDirect Research Breakdown on L Carnitine Examine Androgen receptor density plays a meaningful role in muscle anabolism because it determines how strongly a muscle fiber responds to androgen signaling. Gabriel Alizaidy, MD, MS Frontiers Androgen Receptor Signaling and Metabolic and Cellular Plasticity During Progression to Castration Resistant Prostate Cancer Androgen receptor density plays a meaningful role in muscle anabolism because it determines how strongly a muscle fiber responds to androgen signaling. Gabriel Alizaidy, MD, MS