In RBCs, NADPH are produced exclusively via HMP shunt by the action of G6PD and are responsible to maintain membrane integrity preventing premature destruction. That is why G6PD deficient RBCs are Hereditary Hemolytic Anemias Due to Red Blood Cell Enzyme Disorders Oncohema Key Glutathione Real Time Monitoring of Glutathione in Living Cells Reveals that High Glutathione Levels Are Required to Maintain Stem Cell Function: Stem Cell Reports Frontiers Glutathione: A Samsonian life sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation
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glutathione red blood cells Oxidative Stress Regulatory Pathway (Erythrocyte)