Mast cells are hypersensitive immune cells that release histamine and other inflammatory mediatorsoften in response to oxidative stress, environmental toxins, and immune imbalance. Many patients with MCAS have low levels of glutathione. AAAAI Mast Cell Disorders Committee Work Group Report: Mast cell activation syndrome (MCAS) diagnosis and management Journal of Allergy and Clinical Immunology Can Liposomal Glutathione Support Detoxification and Cellular Energy in Long COVID and ME CFS? RTHM Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification Amazon.com: Allergy Research Group ARG Acetyl Glutathione 100 mg Stabilized Bioavailable Glutathione Antioxidant & Immune System Support Well Absorbed Formula 60 Servings 60 Tablets : Health & Household