Acetaminophen Toxicity: What Pharmacists Need to Know What Happens If You Take Too Much Tylenol? (2026 Facts) Since Tylenol is such a hot topic right now, did you know it depletes glutathione levels? When your body processes Tylenol in the liver, one of the pathways creates a toxic byproduct. To neutralize Tylenol (acetaminophen) is one of the most commonly used painkillers. It is safe for kids, during pregnancy, and while breastfeeding. However, just because it is safe, doesn't mean that it Glutathione, Tylenol & Your Health: What You Should Know