Carnitine Molecule of the Month September 2003 Short Note On Carnitine Shuttle: Fatty acids are oxidized in mitochondria, and synthesized in the cytoplasm. Long chain fatty acids must form an active intermediate, fatty acyl CoA, before being oxidized inside mitochondria. Catherine Mitochondrial transport of long chain fatty acids. While medium and Download Scientific Diagram Pyruvate supported flux through medium chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles: Cell Metabolism Targeting Skeletal Muscle Dysfunction With L Carnitine for the Treatment of Patients With Chronic Obstructive Pulmonary Disease In Vivo